Modeling and computational fluid dynamics simulation of blood flow behavior based on MRI and CT for Atherosclerosis in Carotid Artery

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dc.contributor.authorAttar, Hani
dc.contributor.authorAhmed, Tasneem
dc.contributor.authorRabie, Rahma
dc.contributor.authorAmer, Ayman
dc.contributor.authorKhosravi, Mohammad R.
dc.contributor.authorSolyman, Ahmed
dc.contributor.authorDeif, Mohanad. A.
dc.date.accessioned2024-09-11T19:50:22Z
dc.date.available2024-09-11T19:50:22Z
dc.date.issued2023
dc.departmentİstanbul Gelişim Üniversitesien_US
dc.description.abstractCarotid atherosclerosis is one of the main cardiovascular diseases, widely considered as the main reason for death. Atherosclerosis forms a plaque that impedes blood vessels, and if ruptured, it causes a stroke or heart attack. The treatment protocol for atherosclerosis depends heavily on plaque type, structure, and composition, affecting plaque behavior (stable/unstable) or vulnerability. The fluid-structure interaction between the blood vessels and the blood flow must be examined to study the plaque's behavior. Consequently, this paper aims to reconstruct patient-specific three-dimensional models of the blood vessels for simulation and three-dimensional (3D) Printing, particularly for the carotid artery. In addition, Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) datasets of atherosclerotic vessels are used to reconstruct the 3D model fed into a simulation program to measure the stress, strain, pressure, and velocity to assess the plaque. Five analyses studies were conducted on the constructed blood vessels; Non-pathological Flow in a cylindrical artery, Pathological Flow in a cylindrical artery, Non-pathological Flow in a 2D bifurcating carotid artery, Blood flow analysis in a normal carotid artery, and Blood flow analysis in a stenosed carotid artery. Two validation studies were performed for normal and atherosclerotic arteries. The results agreed with previous well-published work, considering that a 3D realistic model was printed for the vessel. Based on the above, our work provides a simulation environment for predicting atherosclerotic plaque behavior that helps medical specialists choose the proper treatment and preventive medical plans.en_US
dc.description.sponsorshipFawzi from Mechanical Engineering Dept., Cairo University; National Institute of Health (NIH)en_US
dc.description.sponsorshipThe authors would like to thank Waleed, Mohammed Salem and Fawzi from Mechanical Engineering Dept., Cairo University. Also, Dr. Khaled Zakaria of the National Institute of Health (NIH) for providing the MRI dataset, and Dr. Mohammed Donya of the cardiovascular department, Nile Scan for CT data.en_US
dc.identifier.doi10.1007/s11042-023-17765-w
dc.identifier.issn1380-7501
dc.identifier.issn1573-7721
dc.identifier.scopus2-s2.0-85179350866en_US
dc.identifier.urihttps://doi.org/10.1007/s11042-023-17765-w
dc.identifier.urihttps://hdl.handle.net/11363/7619
dc.identifier.wosWOS:001122190800003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofMultimedia Tools And Applicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240903_Gen_US
dc.subjectAtherosclerosisen_US
dc.subjectCarotid arteryen_US
dc.subjectAnsysen_US
dc.subjectHeart attacken_US
dc.subjectAnd Blood vesselsen_US
dc.titleModeling and computational fluid dynamics simulation of blood flow behavior based on MRI and CT for Atherosclerosis in Carotid Arteryen_US
dc.typeArticleen_US

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