Appraisal of the antimicrobial and cytotoxic potentials of nanoparticles biosynthesized from the extracts of Pelargonium quercetorum Agnew

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dc.authoridhttps://orcid.org/0000-0002-0898-3043en_US
dc.authoridhttps://orcid.org/0000-0001-5829-6914en_US
dc.contributor.authorDumlupınar, Berrak
dc.contributor.authorŞeker Karatoprak, Gökçe
dc.contributor.authorFırat, Mehmet
dc.contributor.authorKüpeli Akkol, Esra
dc.date.accessioned2023-08-12T15:14:54Z
dc.date.available2023-08-12T15:14:54Z
dc.date.issued2021en_US
dc.departmentSağlık Bilimleri Fakültesien_US
dc.description.abstractAim: The aim of this study is the synthesis of nanosilver particles (AgNPs) from Pelargonium quercetorum Agnew. (Geraniaceae) and evaluation of the antimicrobial and the cytotoxic potential of AgNPs. Methods: The synthesized AgNPs were evaluated for antimicrobial and anticancer efficacy using the minimum inhibition concentration method and MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide) assay. Results: The AgNPs inhibited approximately 90% the growth of gram-positive Staphylococcus aureus and gram-negative Esherichia coli and yeast Candida albicans pathogens at a concentration of 500 ? g/mL. The synthesized AgNPs showed excellent toxicity in MCF-7 cells, and specifically, pq70 AgNP inhibited the growth of MCF-7 cells by 52% at a concentration of 3.125 ? g/mL. Conclusion: It was determined that the AgNPs, which had been synthesized from extracts that contained a high phenolic composition, were smaller in size, and showed high anticancer and antimicrobial properties.en_US
dc.identifier.doi10.52586/5011en_US
dc.identifier.endpage1096en_US
dc.identifier.issn2768-6701
dc.identifier.issn2768-6698
dc.identifier.issue11en_US
dc.identifier.pmid34856755en_US
dc.identifier.scopus2-s2.0-85121835086en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1089en_US
dc.identifier.urihttps://hdl.handle.net/11363/5289
dc.identifier.urihttps://doi.org/
dc.identifier.volume26en_US
dc.identifier.wosWOS:000727662100012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorDumlupınar, Berrak
dc.language.isoenen_US
dc.publisherIMR PRESS, 112 ROBINSON RD, ROBINSON 112, SINGAPOREen_US
dc.relation.ispartofFrontiers in Bioscience-Landmarken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectPelargonium quercetorumen_US
dc.subjectGeraniaceaeen_US
dc.subjectSilver nanoparticleen_US
dc.subjectAntimicrobialen_US
dc.subjectCytotoxicityen_US
dc.titleAppraisal of the antimicrobial and cytotoxic potentials of nanoparticles biosynthesized from the extracts of Pelargonium quercetorum Agnewen_US
dc.typeArticleen_US

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