Dumlupınar, BerrakŞeker Karatoprak, GökçeFırat, MehmetKüpeli Akkol, Esra2023-08-122023-08-1220212768-67012768-6698https://hdl.handle.net/11363/5289https://doi.org/Aim: The aim of this study is the synthesis of nanosilver particles (AgNPs) from Pelargonium quercetorum Agnew. (Geraniaceae) and evaluation of the antimicrobial and the cytotoxic potential of AgNPs. Methods: The synthesized AgNPs were evaluated for antimicrobial and anticancer efficacy using the minimum inhibition concentration method and MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide) assay. Results: The AgNPs inhibited approximately 90% the growth of gram-positive Staphylococcus aureus and gram-negative Esherichia coli and yeast Candida albicans pathogens at a concentration of 500 ? g/mL. The synthesized AgNPs showed excellent toxicity in MCF-7 cells, and specifically, pq70 AgNP inhibited the growth of MCF-7 cells by 52% at a concentration of 3.125 ? g/mL. Conclusion: It was determined that the AgNPs, which had been synthesized from extracts that contained a high phenolic composition, were smaller in size, and showed high anticancer and antimicrobial properties.eninfo:eu-repo/semantics/openAccessAttribution-NonCommercial-NoDerivs 3.0 United StatesPelargonium quercetorumGeraniaceaeSilver nanoparticleAntimicrobialCytotoxicityArticle26111089109610.52586/5011348567552-s2.0-85121835086Q2WOS:000727662100012Q3