Life quality, depression, and anxiety levels in parents of children with primary immunodeficiency

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dc.authoridhttps://orcid.org/0000-0001-8948-7182en_US
dc.authoridhttps://orcid.org/0000-0003-1017-2052en_US
dc.authoridhttps://orcid.org/0000-0002-4164-4668en_US
dc.contributor.authorKaplan Sarıkavak, Sibel
dc.contributor.authorSarıkavak, Talat
dc.contributor.authorTürkyılmaz Uçar, Özge
dc.contributor.authorAydoğmuş, Çiğdem
dc.contributor.authorÇeliksoy, Mehmet Halil
dc.date.accessioned2024-03-12T21:01:27Z
dc.date.available2024-03-12T21:01:27Z
dc.date.issued2023en_US
dc.departmentSağlık Bilimleri Fakültesien_US
dc.description.abstractBackground: Primary immune deficiencies (PID) encompasses genetic disorders that result in recurrent infections and immune dysregulation, often increasing the risk of malignancies. The aim of this study is to determine the quality of life, depression, and anxiety in parents of children with PID. Methods: Various validated assessmenttools, including theBeck Depression Inventory (BDI), State and Trait Anxiety Inventory (STAI), the 36-item Short Form Survey (SF36), and a demographic form, were employed to gather data from 85 parents of 64 PID patients and 85 parents of 75 healthy children. Results: The findings reveal that parents of PID patients exhibited higher BDI, STAI-S, STAI-T, and fatigue subdomain of SF-36 (p=?.013, p=?.013, p=?.027, p=?.000). Both parents had lower energy levels than the normal population, but mothers experienced higher levels of anxiety and depression. PID mothers' had higher scores than fathers of PID patients with healthy children in BDI, STAI-S, and STAI-T (p=?.002, p=?.010, p=?.001). Mothers of PID patients reported lower scores in RLEP, E/F, EWB, P, and GH compared to fathers (p=?.009, p=?.005, p=?.034, p=?.001, p=?.003). Additionally, the study found that STAI-T influenced all subdimensions of HRQOL. These results highlight the substantial emotional and psychological burden placed on parents caring for children with PID. Conclusion: The study underscores the importance of supporting caregivers to enhance the overall well-being of both parents and children with PID. Such support can potentially alleviate depression and anxiety levels among parents, ultimately improving their quality of life and aiding in the management of children with PID.en_US
dc.identifier.doi10.1111/pai.14068en_US
dc.identifier.endpage9en_US
dc.identifier.issn0905-6157
dc.identifier.issn1399-3038
dc.identifier.issue1en_US
dc.identifier.pmid38284917en_US
dc.identifier.scopus2-s2.0-85182141631en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://hdl.handle.net/11363/7184
dc.identifier.urihttps://doi.org/
dc.identifier.volume35en_US
dc.identifier.wosWOS:001139994600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSarıkavak, Talat
dc.language.isoenen_US
dc.publisherWILEY111 RIVER ST, HOBOKEN 07030-5774, NJen_US
dc.relation.ispartofPEDIATRIC ALLERGY AND IMMUNOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectanxietyen_US
dc.subjectdepressionen_US
dc.subjectparental mental healthen_US
dc.subjectprimary immune deficiencyen_US
dc.subjectquality of lifeen_US
dc.subjectSF-36en_US
dc.titleLife quality, depression, and anxiety levels in parents of children with primary immunodeficiencyen_US
dc.typeArticleen_US

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